Think I have a solution for this, its out of date drivers for the NIC, the ones in use are 3 years old, HP released new drivers in May.
Going to test this in a few of the sites and it will hopefully resolve the issue.
Thank you jah for your interest, I cannot believe I hadn't already checked to see if there was updated drivers already. We have already had to update the BIOS version on all 400 servers to help with noisy fans.