If you want to eliminate the problem for sure... wipe and reload. Problem solved. Yeah, I know it's not the cool and sexy new tool thing to do, but it works.
Here's my personal philosophy. If I have an infection or maybe two that can be eliminated by tools such as malwarebytes I'll do so and them move on... just had this happen two nights ago with one of my kid's machines. Malwarebytes fixed the issue and I've scanned with twop other tools available to me and I feel positive about the state of the PC.
But if I have some massive infection or one that can't be tamed by the tools at my disposal, my goal is to stabilize the system so that I can retrieve any important data and then I wipe and reload. Because at this point, even if things seem OK, I am not sure what the infection has done under the hood and I'd rather take the high road, although, in the short term, the more painful one, and just wipe and reload.
